Daniel L. Silbergeld M.D.

 Daniel  L. Silbergeld M.D.

Specialties and Expertise

Brain Tumors, Gamma Knife, Neurological Surgery


Neurological Surgery, Neurosciences




Gamma Knife Center at Harborview

325 9th Ave., Ste. 44
Seattle, WA 98104
Phone: 206.744.8067|Map It 

Alvord Brain Tumor Center at UWMC

1959 NE Pacific St., 7th Floor, Pacific Tower
Seattle, WA 98195
Phone: 206.598.2282|Map It 

Neurological Surgery Clinic at UWMC

1959 NE Pacific St., 3rd Floor, Surgical Pavilion
Seattle, WA 98195
Phone: 206.598.5637|Map It 

Seattle Cancer Care Alliance at South Lake Union

825 Eastlake Ave. E
Seattle, WA 98109
Phone: 855.557.0555|Map It 


Dr. Silbergeld is the Arthur A. Ward Jr. professor of neurological surgery and is based at the UW Medical Center. He is also an adjunct professor of pathology. He specializes in tumors of the central nervous system, pituitary tumors, epilepsy surgery and radiosurgery with the Gamma Knife. He is board certified in neurological surgery.

His research program focuses on gliomas, a type of brain tumor, and on methods to break the blood/brain barrier to deliver chemotherapy to malignant brain tumors.

Patient Care Philosophy

The vast majority of patients I care for have brain tumors. Some have primary brain tumors (those that start in the brain) while some have metastatic tumors (those that have spread to the brain from other tumors in the body). I believe that caring for patients with tumors necessitates a frank but compassionate discussion about the therapeutic options and the risks, goals and logistics of each of these options. Patients need to be informed about their disease in order to make these tough decisions. A multidisciplinary neuro-oncology team reviews all of my patients. Each patient meets with all potential treatment providers, prior to choosing the treatment options they wish to pursue.

When neurosurgical intervention is the patient’s choice, the goals are to have the patient unharmed by the surgery, to obtain tissue diagnosis and to resect as much of the tumor as is safely possible. These are the goals; this is the order of the goals. I believe that all decisions should be patient-centered, focusing on each patient’s wishes and priorities. Listening to each patient and each patient’s family is a critical part of any decision making. Every patient I care for receives my personal attention and the absolute best care that I can provide.

Personal Interests

Fly fishing, working out and spending time with my family.

Clinical Interests

Brain tumors; epilepsy surgery; functional brain mapping for language, movement and sensation; pituitary tumors, gamma knife radiosurgery.

Research Interests

Glioma invasion and motility; the use of high-intensity focused ultrasound to temporarily disrupt the blood-brain barrier to enable delivery of chemotherapeutic agents to brain tumors.


Univ. of Cincinnati College of MedicineMedical education1984
UW - Dept. of NeurologyFellowshipNeuro-Oncology
UW - Dept. of NeurosurgeryResidencyNeurosurgery
UW - Dept. of SurgeryFellowshipEpilepsy Surgery
UW - Dept. of SurgeryInternshipSurgery


Board Certifications

American Board of Neurological SurgeryNeurological Surgery1995
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A Passion for Life