UW Medicine physicians based at Harborview Medical Center have earned worldwide recognition for their research into life-threatening injury and illness.
Harborview faculty and staff attract nearly $92 million annual in total research dollars from federal and private sources. Through interdisciplinary research conducted at state-of-the-art facilities, Harborview physicians and research scientists work collaboratively to advance patient care in crucial areas:
- Laboratory medicine investigators at Harborview are studying the dynamics and evolution of hepatitis C virus during infection, as well as the immune response and treatment in hepatitis infection.
- Scientists in the Center for AIDS & STD are examining newly identified causes of sexually transmitted infections, the molecular biology and genetics of syphilis, the correlation of chlamydia genomics with clinical disease, and the neurologic complications of syphilis and AIDS. Clinical studies of new AIDS treatments are being conducted in the AIDS Clinical Trials Unit at the Madison Clinic.
- Faculty and trainees in global health are conducting international clinical and epidemiological studies of the biological and epidemiological interactions of AIDS with other infections such as malaria, tuberculosis and herpes simplex virus. Research includes methods for HIV prevention, including prevention of mother-to-child transmission of HIV.
- The Kidney Research Institute, founded in 2008, is a joint venture between Northwest Kidney Centers and UW Medicine. Its purpose is to establish a leading clinical and translational research effort focusing on early detection, prevention and treatment of kidney disease and its complications. The Kidney Research Institute will provide a 360-degree examination of kidney disease with scientists in clinical medicine, pharmacology, genetics, pathology, psychology, education and physiology, working closely with basic scientists in bioengineering, biochemistry, immunology, genomics and other disciplines.
- Trauma researchers are investigating acute lung injury and respiratory infections among immuno-compromised patients, vascular and tissue injury in inflammatory and immune disorders, cell death in molecular mechanisms as a cause of organ failure and wound repair in individuals with abnormal responses to tissue injuries, including burn patients with excessive scarring.
- Orthopaedic scientists in the Biomechanics Laboratory are designing and testing automobile devices that may reduce whiplash injury and other problems.
- Researchers in psychiatry are studying the use of gene therapy to determine how serotonin receptors affect depression, as well as the molecular mechanisms that determine how brain neurons get wired together early in life.
- Neurology researchers are studying brain neuron activity and blood flow to understand stroke, and electrophysiological techniques used to study traumatic brain injury and epilepsy.