The UW Medicine Kidney Genetics Clinic at Harborview Medical Center seeks to serve patients where a genetic kidney disease is known or suspected. It is the first comprehensive clinic focused on genetic kidney diseases on the West Coast, and is a collaborative effort between the Divisions of Nephrology and Medical Genetics in the UW Department of Medicine. We have a multidisciplinary team composed of a nephrologist, medical geneticist, genetic counselor, and provide in-house genetic testing through the UW Center for Precision Diagnostics, a CLIA/CAP-certified lab specializing in genetic testing. In many cases the emphasis will be on assistance with diagnosis and testing for referring providers. The goals are to establish diagnoses at the genetic level in order to best provide information for ongoing patient care. We provide genetic counseling before and after testing to assure that individuals and family members understand the process and the implications of the findings. In addition, the Laboratory works out prior approval for testing with payors. Individual tests for specific genes are available as well as a variety of multi-gene panels depending on the condition of interest.
We strive to build an environment where the needs of patients and their families with often rare conditions are understood and addressed. Our goal is to provide advanced therapy and access to clinical trials where available.
Hours of operation: Third Friday of every month from 8:00 a.m. to 4:30 p.m.
What Conditions are seen in the Kidney Genetics Clinic?
Patients can be referred whenever a family history of kidney disease or other information suggests a genetic cause. We can also assist with screening family members of people with already established genetic kidney diseases. Some conditions may be isolated to the kidney whereas others may be syndromes affecting multiple organ systems. For some patients the focus will be on providing genetic diagnostic services and the patient will return for ongoing care to the referring provider. For others we will provide comprehensive longitudinal care encompassing all aspects of chronic kidney disease management. Kidney diseases that may have a genetic cause include:
- Polycystic kidney disease and other cystic kidney diseases
- Alport syndrome or familial hematuria (blood in the urine)
- Fabry disease
- Tuberous sclerosis
- Some cases of nephrotic syndrome or FSGS
- Some electrolyte disorders
- Some forms of hypertension
- Cystinosis, oxalosis, and other inherited kidney stone conditions