Matthew C. Altman M.D.

Matthew C. Altman M.D.

Specialties and Expertise

Allergy & Immunology, Infectious Diseases




Primary Location

Allergy, Asthma and Immunology Clinic at UWMC

1959 NE Pacific St., 3rd Floor
Seattle, WA 98195
Phone: 206.598.4615|Map It 


Dr. Altman is an assistant professor for the Division of Allergy and Infectious Diseases in the Department of Medicine at UWMC.

Clinical Interests

Investigating the transcriptional changes in blood samples in acute and chronic brucellosis, investigating transcriptional changes in blood and pulmonary samples in viral induced asthma exacerbations, and clinical enrollment and clinical data analysis of patients with hypereosinophilic syndromes and eosinophilic asthma being selected for anti-IL-5 targeted therapy.

Research Interests

Genome transcriptional profiling and genome sequencing technologies are powerful approaches to identify novel biomarkers and mechanisms of immune mediated diseases. These technologies generate huge amounts of biological information and require sophisticated computational tools to understand molecular pathways of the immune system in health and disease. Dr. Altman's research uses these systems scale genomic approaches to investigate the pathogenesis of infectious and immunologic diseases in order to identify both unique and overlapping pathways of disease pathogenesis. Current work is targeted toward the investigation of defects in toll-like receptor signaling pathways, defects in complement pathways, susceptibility to specific zoonotic infections including brucellosis and melioidosis, pathogenesis of asthma development and exacerbations, and pathogenesis of eosinophilic inflammation and eosinophilic diseases.


UW - Allergy & Infectious DiseasesFellowshipAllergy & Clinical Immunology2014
Brigham and Women's HospitalResidencyInternal Medicine2012
Harvard Medical SchoolMedical education2009
Cambridge UniversityMaster2007


Board Certifications

American Board of Internal MedicineAllergy & Immunology2015
American Board of Internal MedicineInternal Medicine2014
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