Dr. Horwitz’s laboratory employs genetic mapping and…
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Patient Care Philosophy
My work, in the clinic and in the lab, is aimed at explaining the genetic origins of disease and applying that information to develop personalized approaches to cancer prevention and treatment.
Travel, technology and world affairs.
Genetic diagnosis of medical disorders, with a particular emphasis on cancer predisposition syndromes.
Human genetics; cancer genetics; clonal evolution of cancer.
|Univ. of Washington, School of Medicine||Medical education||1990
|UW - Dept. of Genetics||Fellowship||
|UW - Division of General Internal Medicine||Internship||
|UW - Division of General Internal Medicine||Residency||
|American Board of Medical Genetics||Clinical Genetics||1996
|American Board of Internal Medicine||Internal Medicine||1993
Dr. Horwitz’s laboratory employs genetic mapping and sequencing strategies to identify genes responsible for familial predisposition to leukemia, lymphoma, and bone marrow failure syndromes. The major focus of his research centers on defining the genetic origins of cancers of the blood and using that as a paradigm for further understanding development.
In related work, Dr. Horwitz’s laboratory has developed a new approach for mapping cell fate during development by inferring the order in which mutations accumulate in somatic tissues. Dr. Horwitz directs the University of Washington School of Medicine Medical Scientist Training Program (MSTP) for concurrent M.D./Ph.D. students. He is the cancer genetics section editor of the Public Library of Science journal PLoS Genetics and former chair of the NIH Genetics of Health and Disease study section. Among his honors, Dr. Horwitz is a recipient of the Presidential Early Career Award for Scientists and Engineers as well as an NIH Director’s Pioneer Award.