Made-to-order nano-cages may become cell cargo shippers
Made-to-order, self-assembling nano-cages, modeled after the 20-sided protective shell on many viruses, have now been designed and constructed at the UW Institute for Protein Design. Many viruses package and deliver their genetic materials into cells in an icosahedron. The sturdy roominess of this geometric structure inspired scientists to create a synthetic version, that, as in nature, can put itself together and take itself apart. Its reversibility makes it a candidate for future research as a cargo container that could enter living cells, then release a vaccine or medication. Read More
Clogged-up immune cells explain smoking risk for TB
New research finding helps to explain why smoking increases an individual’s risk of developing tuberculosis, and also makes the infection worse. Smoking causes vital immune cells—macrophages—to become clogged.
Wearable Artificial Kidney earns FDA fast-track status
The U.S Food and Drug Administration has granted Expedited Access Pathway status to the Wearable Artificial Kidney after the device performed successfully in its initial U.S. clinical trial, which was conducted at UW Medical Center. The WAK is one of the first innovations in dialysis technology in decades; its miniaturized components are worn like a tool belt and connected to patients via catheter.
UW Medicine is among the nation's top institutions in federal research funding. In fiscal year 2015, the UW School of Medicine received approximately $605 million in National Institutes of Health grants and total research funding of more than $1 billion.